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The lower abdomen, flanks, and love-handle areas contain sufficient subcutaneous fat for most patients and reduce the discomfort sometimes reported from upper abdominal injections

The TRIUMPH-4 Phase 3 trial in obesity with knee osteoarthritis later reported 28.7% mean weight loss at 68 weeks with retatrutide 12 mg/week, and identified a dose-related dysesthesia (nerve-tingling) signal in 8.8% of 9 mg and 20.9% of 12 mg patients (Bays et al., 2025)

Each sealed sterile vial contains 10mg of research-grade Retatrutide manufactured and handled under controlled conditions

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