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While challenging the importance of the protein binding hypothesis, it was instead suggested that the key mechanism of cell death involves P450-derived ROS formation during APAP metabolism, which triggers extensive LPO [59, 60]
Overall, there were no differences observed between dose groups, but statistical power was limited due to the small sample size in this study
If the MDL does not resolve through a global settlement, individual cases can return to their home courts for trial
May 2016;16(5):44
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