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The peptide was originally developed to treat growth hormone deficiencies and later gained attention in wellness and performance medicine for its ability to enhance GH release and improve IGF 1 levels
A network meta-analysis of 22 RCTs of 2,258 participants found that lean mass accounted for roughly 25% of total weight lost on GLP-1 drugs, and DXA body-composition substudies report a range of 2640%
At concentration ranges typical to published preclinical protocols, the copper mass delivered by GHK-Cu is orders of magnitude below established acute toxicity thresholds
They add bulk without adding the fiber needed to move that bulk
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