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Furthermore, L-glutamine supports antioxidant defence mechanisms by enhancing glutathione synthesis and stimulating the expression of antioxidant enzymes, thereby helping to combat oxidative stress and manage reactive oxygen species (ROS) generated during periods of heigh stress [68]

The review traced the developmental history of GLP-1 research from the identification of the proglucagon gene in 1982 through to the contemporary landscape of GLP-1-based therapeutics across obesity, cardiovascular disease, NAFLD, neurodegeneration, and cancer biology

Times vary (weeks to months) and effects can be modest or not perceived