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This was the highest dose in the Phase 2 trial (NEJM 2023) and the Phase 3 TRIUMPH-4 trial
7a, TSA also reversed the FFA-induced downregulation of GLP-1R and acetyl-H3 in HepG2 cells
GLP-1 Modulation & Appetite Regulation: A synergistic blend of Berberine, EGCG (Green Tea Extract 50%), CLA, Tesofensine, Chromium, and Cinnamon Extract stimulates GLP-1 secretion and neuropeptide balance, enhancing satiety, insulin sensitivity, and caloric efficiency
In other words, 90% of initial demand from all new patient attempts go unrealized, signifying significant patient leakage
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