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Recently, the extracts and isolated compounds of a number of natural sources in particular botanical sources were well characterized with anti-tyrosinase activities 40,41,42,43,44,45,46,47,48,49,50,51 and have been accepted as popular skin lightening agents 52,53,54,55,56
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Using erastin-treated A549 cells, we measured intracellular Fe 2+ , ROS, lipid peroxide, glutathione, glutamate release into the extracellular space, and cystine uptake
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