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This indicates that the agency viewed the backdating not as an isolated incident but as a symptom of a system that allowed users to manipulate the "time" element of the data record

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The intestinal absorption of carnitine, as well as its renal reabsorption, is primarily mediated by the plasma membrane organic cation transporter novel 2 (OCTN2 SLC22A5) that, among the carnitine-handling transporters, shows the highest affinity toward carnitine