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In one ME/CFS study, significantly lower levels of adrenocorticotropin (ACTH)/cortisol were found (430)
This pathway has also been implicated in a variety of diseases such as cancer and fibrosis [39]
It has been shown that KPT-9274 can promote apoptosis and induce DNA damage in vitro, 312 and significantly reduces tumor proliferation and survival in xenograft models in different tumors, such as pancreatic cancer, 309 pancreatic neuroendocrine tumors, 313 triple-negative breast cancer 311 , and leukemia
Int J Mol Sci [Internet]
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