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Elevated cAMP activates protein kinase A (PKA), which then phosphorylates and activates hormone-sensitive lipase
The T allele was associated with reduced risk of T2D, and increased likelihood of having been a smokerobservations that are consistent with public data
Patients taking anticoagulants should be closely monitored for changes in prothrombin time or INR, and dosage adjustments may be necessary
The inhibition of oxidative stress, inflammation, fibrosis, and induction of natriuresis have been mainly implicated as mechanisms underlying the attenuation of DKD by GLP-1RAs ( Figure 1 )
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