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To address this, future work will include pathway-level validation in gastric tissues and complementary epithelial models, specifically assessing NF-B (p65 nuclear translocation and IB phosphorylation), Nrf2 (nuclear localization and canonical targets such as HO-1 and NQO1), and TGF-/Smad (phosphorylated Smad2/3 and Smad7), alongside pharmacologic inhibition and activation experiments to test necessity and sufficiency
Chen C, Li X, Lv Y, et al
Pan KF, Zhang L, Gerhard M, Ma JL, Liu WD, Ulm K, et al
Jain AB, Kanters S, Khurana R, Kissock J, Severin N, Stafford S
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