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The truth is simple
Collagen decline has begun but hasn't progressed far
In the SURPASS-CVOT trial, tirzepatide met its primary endpoint of non-inferiority to dulaglutide for MACE-3, though it lacks an FDA-approved MACE-reduction indication in the U.S.[2] Post hoc cardiorenal analyses examined outcomes beyond the primary MACE endpoint in patients with concurrent cardiovascular and renal risk [3]
[2] In the US, non-prescription products can be purchased providing up to 1,000 g each, and it is a common ingredient in energy drinks and energy shots, usually at many times the recommended dietary allowance of B 12
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