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This can help you feel satisfied after smaller meals, but it can also contribute to side effects such as nausea, bloating or indigestion

"By adding PYY to the GLP1/GIP/glucagon trio, we hope to rely less on GLP1 and glucagon to drive weight loss, potentially lowering the chance of nausea (from GLP1/PYY) and high blood sugar risk (from glucagon) while keeping the benefits." The medication is still in the experimental/preclinical stage and has not yet been tested in human trials

For example, moving a Monday dose to Sunday can shift the "peak" nausea from Tuesday to Monday evening

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