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10.1016/s0378-4274(99)00230-1 Toxicol
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"Melatonin"
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When supplements make more sense than medications Supplements are a reasonable starting point for people who want mild appetite support without medical intervention, those who do not qualify for GLP-1 medications based on BMI requirements , individuals who tried medications but could not tolerate the side effects, people who prefer a natural approach before considering pharmaceuticals, and those who have already achieved their target weight with medications and want gentler support during the maintenance phase
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human clinical data is limited
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