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The bloodbrain barrier (BBB) ingests iron through transferrin on brain capillary endothelial cells, and then transports it into the cerebral cytoplasm through astrocytes or through divalent cation-binding protein (DMT1) and maintains iron an approximately saturated steady state in the brain (Belaidi and Bush, 2016), thereby maintaining the normal physiological function of the nervous system
However, ingestion of such high doses of glutathione is often accompanied by undesirable side effects such as nausea and/or other negative effects (e.g., taste aversion)
NICE guidance suggests considering B12 status assessment in older adults presenting with cognitive decline, unexplained anaemia, or neurological symptoms
Researchers and consumers should be aware that the quality and purity of GHK-Cu products can vary significantly between suppliers
