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What Actually Works Heres what the current evidence shows about cagrilintide and CagriSema: Weight loss: REDEFINE 1 participants lost over 20% of body weight on average over 68 weeks meaningfully more than semaglutide alone

10.1080/0964704X.2011.623917 61

These findings support more research, but they do not show that 5-Amino-1MQ causes weight loss, more energy, or better health in people