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Likewise, PET-CT scans of mice fed a high-fat diet (HFD) showed that metformin increased glucose uptake on the basolateral side of the intestine, leading to enhanced glucose tolerance in a manner that depended on the dosage (Tobar et al., 2023)
"Increases in GLP-1RA dispensing were greatest for females, highlighting the importance of educating patients and prescribers on sex-specific safety risks [eg, concerns during pregnancy]," the team noted
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People with BMI 35+, type 2 diabetes, or urgent medical need for weight loss should discuss standard dosing protocols with their doctor first
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