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Thanks for sharing Perhaps the emphasis should be on metformin - pharmacoeconomically drugs that are almost free are often left out of the conversation or just mentioned as oh by the way metformin does it too "This cohort study of more than 1.6 million patients with type 2 diabetes (T2D) who had no prior diagnosis of 13 [0beisity-Associated Cancer] OACs found that patients with T2D treated with GLP-1RAs vs insulin had a significant risk reduction in 10 of 13 OACs, including esophageal, colorectal, endometrial, gallbladder, kidney, liver, ovarian, and pancreatic cancer as well as meningioma and multiple myeloma

Results older than six months are typically repeated before initiating treatment, since metabolic markers can change meaningfully in that window