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Side effects vary by peptide most commonly a mild, temporary redness or irritation at the injection site

Semaglutide-related nausea is mild to moderate, follows a predictable 3-7 day peak after each dose, improves with meal adjustments and anti-nausea medications, and resolves within 8-12 weeks of treatment

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Be sure to tell them if any of the following factors apply to you: low vitamin B12 heart failure liver problems planned surgery upcoming imaging tests, such as an X-ray or CT scan kidney damage age 65 years or older hypoglycemia (low blood sugar) previous allergic reaction to Janumet or any of its ingredients pregnancy breastfeeding alcohol consumption Like most medications, Janumet and Janumet XR may cause mild or serious side effects