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The cortisol connection Chronic stress elevates cortisol, and elevated cortisol suppresses both testosterone production and sexual desire

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39 In the SCALE trial, which enrolled 3,731 overweight or obese adults, liraglutide 3.0 mg daily was shown to reduce both systolic and diastolic BP, with average delta of 2.8 mmHg (95% CI [3.56, 2.09) and 0.9 mmHg (95% CI [1.41, 0.37), respectively

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The cGAS-STING pathway is a major cytosolic DNA-sensing pathway, where cGAS detects foreign DNA and synthesizes cyclic GMP-AMP, which then binds to and activates STING

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Enhances angiogenesis (formation of new blood vessels)

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