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Among them, the glutamate produced by the decomposition of glutamine via GLS not only provides the raw material for the synthesis of GSH but is also further metabolized into -ketoglutarate (-KG) in the mitochondria under the action of glutamate dehydrogenase (GLUD1) or transaminases and then enters the tricarboxylic acid cycle to produce ATP [29]

A growing body of evidence suggests that nanoscale materials can trigger Ca 2+ -dependent eryptosis in mature erythrocytes obtained from various species in a time- and dose-dependent fashion [450]

This is followed by osteoclast activation, which breaks down bones

[14] Atalay F, Odabasoglu F, Halici M, et al