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Mechanism: Actin polymerization accelerates cell migration to injury sites
Interestingly, TFAM and mtDNA form a self-regulatory positive feedback loop: TFAM knockout triggers mtDNA depletion, while reduced mtDNA copy numbers further promote TFAM degradation [54,55,56] (Table 1)
Extremely small or large individuals may adjust slightly, but most researchers use standard fixed doses successfully
Therefore, strategies to combat skeletal fragility are essential to maintain human bone health
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