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For optimal results, patients are advised to apply the cream twice daily to the affected area, massaging it in until it is fully absorbed
Int J Clin Pharmacol Res 1990;10:123-8
As previously described under the subsection of IGF-1R, the authors investigated the let-7 function in glucose metabolism using inducible let-7 transgenic mice model and found that let-7 overexpression induced glucose intolerance by targeting multiple components of the insulin-PI3K-mTOR signaling pathway including IRS-2, IGF-1R, and INSR
Thylen C, Wahlqvist J, Haettner E, Sandgren O, Holmgren G, Lundgren E
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