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Any treatment plan involving these agents should include: Regular blood tests (glucose, HbA1c, IGF-1, lipids, liver function, renal function) Documented informed consent regarding off-label or investigational use Dietitian input to monitor nutritional status, particularly during periods of rapid weight loss or reduced appetite Reconciliation of all concomitant medicines , including over-the-counter products and supplements, to minimise interaction risks Clear escalation pathways if side effects arise, including urgent review for severe abdominal pain, dehydration, or hypoglycaemia Ongoing review by a named responsible clinician Reporting of any suspected adverse effects via the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk) Your health and safety are best protected by working transparently within the NHS or a regulated private medical setting, with full disclosure of all medicines prescribed or otherwise that you are taking
(2021) demonstrated that fluoxetine was capable of decreasing serum testosterone levels as well as the height and diameter of the varicocele epithelium, increasing collagen fiber deposition in testicular tissue, and inducing a positive immune response to B-cell lymphoma-2 associated X protein
It is mainly used as treatment for type 2 diabetes, but it has recently been prescribed as an anti-obesity medication for long-term weight management
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