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What the Research Shows The approval was based on impressive results from the SURMOUNT-OSA clinical trials involving 469 adults: For people NOT using CPAP machines: Tirzepatide reduced breathing interruptions by 25 events per hour Placebo only reduced interruptions by 5 events per hour 42% achieved remission or mild symptoms after one year For people USING CPAP machines: Tirzepatide reduced breathing interruptions by 29 events per hour Placebo only reduced interruptions by 6 events per hour 50% achieved remission or mild symptoms after one year Beyond Sleep Apnea While sleep apnea research is most advanced, early evidence suggests GLP-1 medications may help with other sleep problems too: Reduced insomnia symptoms Less tossing and turning at night Improved deep sleep quality Better daytime energy levels Who Can Benefit From GLP-1 Therapy for Sleep
If another option may better meet your needs, we may discuss alternatives such as Tirzepatide , which is another medication available through our Medical Weight Loss and Wellness program
The most important head-to-head data comes from the SUSTAIN 7 trial, published in The Lancet Diabetes & Endocrinology in 2018
With each percentage of fat reduction, we see a meaningful modification in disease outcomes
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