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2025 Oct 14:e05653

The antioxidant activity of GSH intermediated via thiol (-SH) of its cysteine residue upon its interaction with ROS or electrophiles and the GSH oxidized to GSSG (oxidized Glutathione), the GSSG will reduce to GSH by Glutathione reductase (GR), the activity of GR is therefore very important to keep the antioxidant power of mammalian cells, while GSH/GSSG ratio is an indicator for redox balance in the cell

Many people maintain results with periodic maintenance sessions rather than expecting a one time permanent change

But 23% is still a meaningful step up from what semaglutide (Wegovy) achieves on its own, where the average tends to land around 14 to 15%