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Lipid metabolism is key for ferroptosis, which is driven by the accumulation of lipid peroxides resulting from the oxidation of polyunsaturated fatty acids (PUFAs) (24)
Abstract Objective Oxidative stress plays a pivotal role in the pathogenesis of Down syndrome (Trisomy 21), as chromosome 21 harbors multiple genes involved in redox homeostasis and antioxidant defense mechanisms
Membrane skeleton modulates erythroid proteome remodeling and organelle clearance
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