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It solely affects the mucosa ( An increasing amount of evidence derived from both clinical investigations and experimental models indicates that oxidative stress signaling contributes to the development of IBD through various functional pathways

Twenty l of filtered MTT solution (5 mg/ml in PBS) was added to each well, after which the plates were incubated for an additional 4 h

This happens because certain MTHFR mutations (C667T and A129C) lower the amount of active folate being produced in the body, and the use of vitamin B12 requires the active form of folate

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