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The researchers built study cohorts with information taken from the U.S
The TME significantly impacts melanomas transcriptomic landscape, meaning nano-immunotherapy not only induces tumor cell death but may also drive shifts in melanoma cell states and meta-programs ( Single-cell RNA sequencing has identified the first cancer cell-specific meta-program linked to T cell exclusion and resistance to immunotherapy, characterized by increased levels of CDK4, MYC, and CDK7 (5860)
Zhao L, Li Z, Vong JSL, Chen X, Lai HM, Yan LYC, et al
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