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Similarly, therapeutic VB6 dosages for patients with pyridoxine-dependent epilepsy typically range from 15 to 30 mg/kg/day in infants, with neonates receiving up to 200 mg/day and adults requiring doses as high as 500 mg/day [159]
This is a precautionary signal, not an established risk
For metabolite clustering analysis, average linkage hierarchical clustering was performed in the Statistical Analysis module of MetaboAnalyst 6.0 using Euclidian distance as a similarity metric
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