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The Role of GLP-1 Medications In recent years, the widespread use of GLP-1 and GIP medications has revolutionized the medical management of obesity and inflammation

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However, another group found that the presence of the T1D-linked genetic variant of rs2281808 is associated with reduced SIRP expression in CD8+ T cells, an increased effector state with a lower T cell activation threshold, and a reduction in gene expression associated with long-term functional memory T cell formation (84)

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A mean increase in HR of 1.86 beats/min was reported in a meta-analysis including available data from randomized controlled trials testing GLP-1 agonists against placebo in patients with T2D [53]

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