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Almandoz explained that when an individual loses a significant amount of weight, many other functions and reactions within the body change as wellreduced muscle mass can result in increased risk of falling, appetite changes can result in malnutrition, and existing frailty can be exacerbated

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doi:10.1177/20420188231222367 Gao H, Zhao Q, Tang S, Li K, Qin F, Song Z, Pan Y, Jin L, Zhang Y

2.5 Statistical analysis We applied 1:1 propensity score matching (PSM) using greedy nearest neighbor matching with a 0.1 caliper to balance baseline characteristics between the tirzepatide and control groups