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When ATP rises, the ATP-sensitive potassium channel in pancreatic beta cells closes, which then triggers the release of insulin.[ref] Genetic variants in KCNJ11 can decrease the beta cells insulin response to blood glucose

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For example, activating dopaminergic VTA neurons increases operant responses for a food reward [94], while inhibiting these neurons by activating GABAergic VTA interneurons has the opposite effect [95]

As with GH, subjects showed an increase in lean body mass and a decrease in body fat (particularly abdominal visceral fat)