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Although the mean values for each of the alpha diversity measures were often largest for the 5A-1MQ-treated group switched from WD to LD relative to all other groups (Fig

doi:10.1016/j.bmcl.2018.07.009

- People with active or recent cancer history (the trial record contains a small number of cancers in the 12-week oral arm

The advantages of GLP-1 agonists include substantial clinical trial data supporting their efficacy and safety, FDA approval for weight management in certain populations, proven results with many users losing 15-20% or more of body weight, and effects on appetite that make caloric restriction feel natural