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The mechanism of action of tirzepatide involves enhancing insulin secretion and suppressing glucagon release, which can lead to metabolic changes that may indirectly influence heart rate
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The FDA updated both the Mounjaro and Zepbound labels in November 2024 to add pulmonary aspiration during elective procedures as a postmarketing adverse reaction, and the UK MHRA issued a corresponding Drug Safety Update on the same concern
Some GLP-1 medicines are available as oral tablets, but only for diabetes treatment
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