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This difference in potency means that patients stepping down from semaglutide to liraglutide should expect some degree of weight regain unless caloric deficit is maintained through behavioral strategies
Tirzepatide can cause dehydration through reduced food and fluid intake, nausea, and changes in digestion
Real-world outcomes suggest that patients receiving medication alonewithout structured supportoften struggle to maintain results long-term
doi:10.1210/jc.2015-1176 Hansen MS, Wlfel EM, Jeromdesella S, et al
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