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In more detail, when discussing product integrity the main things to consider are ensuring that the device does not leak, that there is no weight loss (indicating an evaporation of solvent and therefore a change in the potency of the drug product) and that the extractables and leachables profiles of the device materials are within regulatory limits
White WB, Bakris GL, Bergenstal RM, Cannon CP, Cushman WC, Fleck P, Heller S, Mehta C, Nissen SE, Perez A, Wilson C, Zannad F
Topical application Topical use doesn't consume reconstituted injectable solution but rather uses dedicated topical preparations
We discuss this risk and prevention techniques during the free consultation with our doctors
