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Jun 2010;38(3):169-178
Immune activation and mitochondrial dysfunction in both central and peripheral immune cells (like microglia in the brain and monocytes in blood) are implicated in these cognitive complications ( 4.2.1 Neuroinflammation after surgery Surgical trauma induces a rise in pro-inflammatory cytokines (IL-6, TNF-) that can cross the blood-brain barrier or signal via vagal pathways to activate brain endothelium and microglia (128, 129)
Bile is essential for detoxification, digestion, absorption of fats and fat-soluble vitamins, and many more important body functions (12)
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