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Semaglutide reduced body weight by 24% and decreased cumulative food intake by 33% in the DIO mouse model: Semaglutide decreased overall adiposity by 57% in the DIO mouse model: Semaglutide improved glucose tolerance during an oral glucose challenge in the DIO mouse model: Semaglutide decreased liver lipids (triglycerides, cholesterol, NEFA) in the DIO mouse model: Importantly, our DIO mouse model is generated in-house by feeding a diet closely resembling the fat content of the western diet
[Research Gate] Philp, D., et al
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![GLP-1 Weight-Loss Medication Glucagon-like peptide-1 (GLP-1) receptor agonists (semaglutide [Wegovy, Ozempic, Rybelsus]) and dual incretin agonists (tirzepatide [Zepbound, Mounjaro]) are popular treatments for obesity. The authors discuss the kind of](https://lookaside.fbsbx.com/lookaside/crawler/media/?media_id=1050961973852737)
