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The linear peptide is covalently bound to a C20 fatty diacid moiety at the side chain of the Lys20 amino acid ( Figure 2 depicts the amino acid sequence of tirzepatide in comparison to GLP-1, GIP as well as the GLP-1RA exendin-4 (exenatide)

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Similarly, in rats injected with monoclonal antibodies (mAbs) in the hippocampus, pre-treatment with liraglutide significantly protected from the mAbs-induced damage of spatial memory and long-term potentiation (51)

The Initial Visit (A Comprehensive History and Physical done by the Doctor with general blood testing, drawn at the time of the visit, and 4 weekly Injections of Semaglutide