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Phase 2 clinical trials involved 338 adults with obesity (BMI 30 or more) and overweight (BMI of 2729.99) with one or more weight-related conditions such as high blood pressure, high cholesterol levels, heart disease, and type 2 diabetes
The other form of AMACR deficiency is an early onset disorder characterized by severe liver abnormalities
(Note: this concerns only scientific observations within research context)
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