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Presented for research literature review only Dirr HW et al
Testosterone keeps male characteristics dominant oestrogen, which is present in small amounts, can stimulate breast tissue When the amount of oestrogen becomes higher, or testosterone drops, breast tissue can start to grow
PMID 24091055
Because of that, the NICE recommendations lean towards individualised care: tailoring the dose, frequency and delivery method, following people up at around three months, and reviewing sooner if symptoms are severe or if someone is pregnant or breastfeeding
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