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Oxidative stress, UV radiation, and enzymatic degradation (via elastase) progressively destroy elastin fibers without replacement
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i 2+ K : Beta-2 receptor stimulation has been shown to stimulate calcium-activated potassium (KCa) channels in airway smooth muscle by both PKA-induced phosphorylation, and membrane-delimited Gs pathways (Kume et al, 1994)
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