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[30] The discovery of GLP-1's extremely short half-life meant that it was impossible to develop into a drug
In another study that examined the molecular mechanisms behind the effects of liraglutide on oxidized low-density lipoprotein in endothelial cells [68], liraglutide was found to suppress LDL-induced immune cell adhesion to the endothelial cells by inhibiting the expression of vascular adhesion molecules including E-selectin and VCAM-1 both of which have been related to the development of atherosclerosis [68,69,70,71] (refer to Figure one)
Elevation of ISG15 promotes diabetic kidney disease by modulating renal tubular epithelial cell pyroptosis
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