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The study participants also reported improvements in sleep quality, with 58% noting better sleep continuity and reduced morning fatigue
In humans, immunohistochemistry using a monoclonal antibody showed that the GLP-1 receptor protein is expressed in the pancreas, in smooth muscle cells of the kidney, lung, and gastrointestinal (GI) tract, and in myocytes of the heart [16]
Collectively, these findings highlight cotadutides dual benefits for glycemic control and liver health, supporting its further development for T2D, obesity, and NASH treatment [85]
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