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Cagrilintide is a 39amino-acid peptide with structural modifications (including an N-terminal fatty diacid chain) designed to improve stability and reduce fibril formation compared with native amylin

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Multiple Phase 3 clinical trials in human subjects show sustained weight loss averaging 15-22% of body weight at higher doses, along with major HbA1c reductions, improved glycemic control, visceral fat reduction, and better lipid profiles

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