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The overall cardiometabolic benefit of GLP-1RA rapidly expanded beyond the T2DM population, with the Semaglutide Effects on Cardiovascular Outcomes in People with Overweight or Obesity (SELECT) trial describing MACE reduction in the population with overweight and obesity, even in the absence of T2DM [14]
Complete resection is an important prognostic factor
Retatrutide improves glucose metabolism, lipid profiles, and liver fat through incretin and glucagon pathways
However, at this point it should be noted that different incretin drugs are characterized by different pharmacokinetics, and therefore, they are taken by patients at different time intervals
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