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Instead of promoting GSH-conjugation reactions, cysteine-containing GSTs (Cys-GSTs) are able to perform deglutathionylation reactions similarly to glutaredoxins but the targets are usually different since glutaredoxin substrates are mostly oxidized proteins and Cys-GST substrates are metabolites
Myth: "I can get all the glutathione I need from food." Fact: While some foods contain glutathione, it is poorly absorbed through the digestive tract
Senthebane DA, Jonker T, Rowe A, Thomford NE, Munro D, Dandara C, et al
Mancias JD, Wang X, Gygi SP, Harper JW, Kimmelman AC
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