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[8] They found no acute toxicity at doses up to 10 mg/kg
This review focuses on recent studies, demonstrating the actions of local IGF-I/IGF-IR signaling in (a) supporting skeletal development and remodeling, (b) cross-talk with other autocrine/paracrine pathways in the bone, (c) mediating cell-cell interactions between various types of skeletal cells, and (d) integration with systemic signals to produce skeletal anabolism
It has also been shown to exert similar effects, including improved heart function and enhanced muscle mass [4, 5]
187 Investigators have therefore hypothesized that aerosols of hyaluronic acid inhaled daily may protect against lung elastic fiber injury
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