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With tirzepatide (Zepbound), the effect is even more pronounced
Zhang HY, Yang GH, Chen HJ, Wei B, Ke Q, Guo H, Ye L, Bu H, Yang K, Zhang YH
According to a clinical primer published in the American Heart Association journal Circulation, semaglutide has been associated with lean mass making up a large share of total weight lost, by some trial estimates approaching 40 percent, and tirzepatide has shown a similar pattern at roughly a third of weight lost
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