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Urgent need of treatment for AD and PD Despite considerable advances, existing AD and PD treatments primarily address the symptoms rather than the cause
[,,] Studies have shown that serum carnitine levels in obesity and metabolic syndrome decrease following insulin resistance
Succinate dehydrogenase supports metabolic repurposing of mitochondria to drive inflammatory macrophages
A small but growing body of evidence has explored this question: Castaeda et al., 2025 ( Lancet Obstetrics, Gynaecology & Womens Health ) Postmenopausal women treated with tirzepatide who were also using menopausal hormone therapy lost approximately 35% more weight than non-users
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